This paper provides a theoretical and numerical investigation

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Chloromethyl PolyHIPE was shown to be an excellent support for batch and flow through Suzuki cross coupling reactions. A remarkably high yield of pure biaryl product was obtained using PolyHIPE in cubic form and an electron rich boronic acid. In comparison to polymer beads, PolyHIPE was found to be a much more efficient support in both batch and continuous flow modes.

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